HLA-B, chr6:31321649-31324965 +/- 50000 base pairs
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Most significant meta-analysis in this region
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Polymorphism Location (hg19) Gene Ethnicity # Samples # Studies Allele contrast 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs3997869 - HLA-B All: C 105,041 14 C vs. T - - 1.18 (1.13-1.24) 37 (0-67) 1.94e-11
Meta_image?name=rs3997869

All meta-analyses in this region

Polymorphism Location (hg19) Gene Ethnicity # Samples # Studies Allele contrast 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs2844558 chr6:31340433 RNU6-283P [+2416bp] C - 10 T vs. C 0.417 (C) 0.325 (C) <1 (-) 1 (-) <0.05
rs9378249 chr6:31327701 HLA-B [+2736bp] C - 5 T vs. G 0.058 (G) 0.1 (G) >1 (-) 0 (-) <0.05
rs9265477 chr6:31297092 HLA-B [-24557bp] C - 4 T vs. C 0.458 (C) 0.492 (C) <1 (-) 55 (-) <0.05
rs7772305 chr6:31328886 HLA-B [+3921bp] C - 7 A vs. G - - >1 (-) 0 (-) <0.05
rs1634754 chr6:31278398 HLA-C [+38491bp] C - 8 T vs. C 0.5 (C) 0.342 (C) <1 (-) 49 (-) <0.05
rs13213558 chr6:31327833 HLA-B [+2868bp] C - 3 A vs. G 0.075 (A) 0.175 (A) >1 (-) 13 (-) <0.05
rs2523532 chr6:31350550 RNU6-283P [+12533bp] C - 12 A vs. C 0.208 (C) 0.033 (C) <1 (-) 36 (-) <0.05
rs2853967 chr6:31366472 MICA [-4884bp] C - 10 T vs. C - - >1 (-) 0 (-) <0.05
rs3763288 chr6:31370367 MICA [-989bp] C - 10 A vs. G 0.05 (A) 0.117 (A) <1 (-) 0 (-) <0.05
rs115959678 chr6:31326080 HLA-B [+1115bp] C - 5 T vs. C 0.042 (C) 0.108 (C) >1 (-) 52 (-) <0.05
rs9468942 chr6:31274441 HLA-C [+34534bp] C - 3 A vs. G - 0.017 (A) >1 (-) 0 (-) <0.05
rs73390208 chr6:31326131 HLA-B [+1166bp] C - 6 T vs. C 0.225 (T) 0.375 (T) <1 (-) 0 (-) <0.05
rs9266636 chr6:31347033 RNU6-283P [+9016bp] C - 12 A vs. G 0.267 (G) 0.383 (G) >1 (-) 0 (-) <0.05
rs9266637 chr6:31347045 RNU6-283P [+9028bp] C - 12 C vs. G 0.267 (G) 0.375 (G) >1 (-) 0 (-) <0.05
rs4397267 chr6:31312570 HLA-B [-9079bp] C - 4 T vs. C 0.242 (C) 0.383 (C) >1 (-) 0 (-) <0.05
rs9394070 chr6:31366295 MICA [-5061bp] C - 10 A vs. C - - <1 (-) 0 (-) <0.05
rs115999992 chr6:31348987 RNU6-283P [+10970bp] C - 8 A vs. T 0.033 (A) - >1 (-) 60 (-) <0.05
rs9295987 chr6:31349844 RNU6-283P [+11827bp] C - 11 A vs. G 0.067 (G) 0.05 (G) >1 (-) 0 (-) <0.05
rs9264983 chr6:31281231 HLA-B [-40418bp] C - 4 A vs. G 0.258 (A) 0.2 (A) >1 (-) 23 (-) <0.05
rs202154837 chr6:31362737 MICA [-8619bp] C - 8 T vs. C - - >1 (-) 0 (-) <0.05
rs76703505 chr6:31274666 HLA-C [+34759bp] C - 11 T vs. C 0.067 (T) 0.358 (T) <1 (-) 9 (-) <0.05
rs9265486 chr6:31297286 HLA-B [-24363bp] C - 3 T vs. C - - <1 (-) 67 (-) <0.05
rs9266439 chr6:31337804 RNU6-283P [-107bp] C - 12 A vs. G 0.358 (G) 0.358 (G) <1 (-) 0 (-) <0.05
rs35278939 chr6:31319780 HLA-B [-1869bp] C - 7 A vs. G 0.167 (A) 0.117 (A) <1 (-) 0 (-) <0.05
rs9266064 chr6:31319457 HLA-B [-2192bp] C - 4 T vs. C 0.483 (T) 0.4 (C) <1 (-) 8 (-) <0.05
rs4947311 chr6:31326166 HLA-B [+1201bp] C - 7 T vs. C 0.342 (T) 0.167 (C) <1 (-) 0 (-) <0.05
rs9266446 chr6:31338126 RNU6-283P [+109bp] C - 12 T vs. C 0.358 (C) - <1 (-) 0 (-) <0.05
rs9266638 chr6:31347057 RNU6-283P [+9040bp] C - 12 T vs. C 0.267 (T) 0.375 (T) <1 (-) 0 (-) <0.05
rs2507968 chr6:31372718 MICA C - 10 A vs. G - - <1 (-) 11 (-) <0.05
rs4335019 chr6:31275560 HLA-C [+35653bp] C - 11 T vs. C 0.075 (C) 0.35 (C) >1 (-) 19 (-) <0.05
rs59440261 chr6:31371071 MICA [-285bp] C - 9 A vs. C 0.042 (A) - <1 (-) 0 (-) <0.05
rs6941926 chr6:31281229 HLA-B [-40420bp] C - 6 C vs. G 0.05 (G) - <1 (-) 0 (-) <0.05
rs7760988 chr6:31273030 HLA-C [+33123bp] C - 11 T vs. C 0.075 (T) 0.267 (T) <1 (-) 15 (-) <0.05
rs6926927 chr6:31273992 HLA-C [+34085bp] C - 11 A vs. G 0.075 (A) 0.267 (A) <1 (-) 15 (-) <0.05
rs9394056 chr6:31273333 HLA-C [+33426bp] C - 11 A vs. G 0.075 (G) 0.267 (G) >1 (-) 16 (-) <0.05
rs9368679 chr6:31272729 HLA-C [+32822bp] C - 11 T vs. C 0.075 (T) 0.267 (T) <1 (-) 16 (-) <0.05
rs9357125 chr6:31273578 HLA-C [+33671bp] C - 11 T vs. C 0.075 (T) 0.267 (T) <1 (-) 15 (-) <0.05
rs116488202 chr6:31344916 RNU6-283P [+6899bp] C - 9 T vs. C 0.033 (T) - >1 (-) 55 (-) <0.05
rs9368680 chr6:31272844 HLA-C [+32937bp] C - 11 C vs. G 0.075 (C) 0.267 (C) <1 (-) 16 (-) <0.05
rs6930944 chr6:31274036 HLA-C [+34129bp] C - 11 A vs. G 0.075 (G) 0.267 (G) >1 (-) 14 (-) <0.05
rs5006724 chr6:31337850 RNU6-283P [-61bp] C - 12 T vs. C 0.342 (T) 0.358 (T) >1 (-) 0 (-) <0.05
rs9368678 chr6:31272463 HLA-C [+32556bp] C - 11 T vs. C 0.075 (C) 0.267 (C) >1 (-) 16 (-) <0.05
rs34821683 chr6:31361974 MICA [-9382bp] C - 9 T vs. C 0.117 (C) 0.167 (C) >1 (-) 0 (-) <0.05
rs9368674 chr6:31271758 HLA-C [+31851bp] C - 11 A vs. G 0.075 (A) 0.267 (A) <1 (-) 16 (-) <0.05
rs9368673 chr6:31271757 HLA-C [+31850bp] C - 11 T vs. C 0.075 (C) 0.267 (C) >1 (-) 16 (-) <0.05
rs2442723 chr6:31320164 HLA-B [-1485bp] C - 4 A vs. G - - <1 (-) 47 (-) <0.05
rs75430636 chr6:31347630 RNU6-283P [+9613bp] C - 11 T vs. C 0.042 (T) 0.083 (T) <1 (-) 0 (-) <0.05
rs76188215 chr6:31347583 RNU6-283P [+9566bp] C - 11 T vs. C 0.058 (T) 0.067 (T) <1 (-) 0 (-) <0.05
rs78948882 chr6:31347095 RNU6-283P [+9078bp] C - 11 T vs. C 0.058 (T) 0.083 (T) <1 (-) 0 (-) <0.05
rs4991647 chr6:31337671 RNU6-283P [-240bp] C - 12 A vs. G 0.358 (A) 0.367 (A) >1 (-) 0 (-) <0.05

Association studies for this region [+]