HLA-C, chr6:31236526-31239907 +/- 50000 base pairs
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Most significant meta-analysis in this region
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Polymorphism Location (hg19) Gene Ethnicity # Samples # Studies Allele contrast 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs2853923 chr6:31265737 HLA-C [+25830bp] All: C 103,235 14 A vs. G 0.492 (A) 0.442 (A) 1.07 (1.04-1.11) 0 (0-47) 9.90e-06
Meta_image?name=rs2853923

All meta-analyses in this region

Polymorphism Location (hg19) Gene Ethnicity # Samples # Studies Allele contrast 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs2524119 chr6:31229404 HLA-C [-7122bp] All: C 80,278 5 T vs. C 0.475 (T) 0.333 (T) 1.10 (1.04-1.16) 21 (0-66) 4.18e-04
rs114343342 chr6:31210006 HLA-C [-26520bp] C - 12 A vs. G 0.017 (A) - >1 (-) 0 (-) <0.05
rs3095244 chr6:31214576 HLA-C [-21950bp] C - 10 T vs. C 0.45 (T) 0.325 (T) >1 (-) 0 (-) <0.05
rs3134757 chr6:31214583 HLA-C [-21943bp] C - 10 A vs. G 0.417 (A) 0.292 (A) >1 (-) 0 (-) <0.05
rs3130411 chr6:31216052 HLA-C [-20474bp] C - 10 A vs. G 0.408 (G) 0.308 (G) <1 (-) 0 (-) <0.05
rs150314604 chr6:31201376 HCG27 [+29631bp] C - 12 T vs. C - - >1 (-) 0 (-) <0.05
rs144478677 chr6:31202581 HCG27 [+30836bp] C - 12 C vs. G - - >1 (-) 0 (-) <0.05
rs116615123 chr6:31203923 HCG27 [+32178bp] C - 12 A vs. G 0.033 (G) 0.025 (G) <1 (-) 0 (-) <0.05
rs9264125 chr6:31211436 HLA-C [-25090bp] C - 12 T vs. C 0.433 (T) 0.492 (T) >1 (-) 18 (-) <0.05
rs3130688 chr6:31210216 HLA-C [-26310bp] C - 12 T vs. C 0.408 (C) 0.308 (C) <1 (-) 26 (-) <0.05
rs115193934 chr6:31276659 HLA-C [+36752bp] C - 4 C vs. G - 0.158 (C) >1 (-) 0 (-) <0.05
rs3095241 chr6:31215635 HLA-C [-20891bp] C - 10 A vs. C 0.408 (A) 0.308 (A) >1 (-) 0 (-) <0.05
rs9264223 chr6:31221992 HLA-C [-14534bp] C - 4 T vs. G - - <1 (-) 0 (-) <0.05
rs9264245 chr6:31222694 HLA-C [-13832bp] C - 4 T vs. G - - <1 (-) 0 (-) <0.05
rs3095242 chr6:31215556 HLA-C [-20970bp] C - 10 T vs. C 0.408 (T) 0.325 (T) >1 (-) 0 (-) <0.05
rs9264186 chr6:31220017 HLA-C [-16509bp] C - 9 A vs. G 0.408 (G) 0.45 (A) <1 (-) 0 (-) <0.05
rs3130431 chr6:31219342 HLA-C [-17184bp] C - 10 A vs. G 0.417 (A) 0.325 (A) >1 (-) 1 (-) <0.05
rs6908171 chr6:31270735 HLA-C [+30828bp] All: C 103,235 14 A vs. C - - 0.94 (0.91-0.98) 14 (0-52) 5.38e-04
rs3130418 chr6:31217403 HLA-C [-19123bp] C - 10 T vs. C 0.408 (T) 0.308 (T) >1 (-) 0 (-) <0.05
rs3095248 chr6:31209288 HLA-C [-27238bp] C - 12 T vs. C 0.433 (T) 0.383 (T) >1 (-) 29 (-) <0.05
rs2394906 chr6:31216558 HLA-C [-19968bp] C - 10 A vs. T 0.425 (A) 0.3 (A) >1 (-) 0 (-) <0.05
rs3130416 chr6:31216918 HLA-C [-19608bp] C - 10 A vs. T 0.408 (T) 0.317 (T) <1 (-) 0 (-) <0.05
rs116780006 chr6:31199765 HCG27 [+28020bp] C - 12 T vs. C 0.033 (T) - >1 (-) 0 (-) <0.05
rs3130534 chr6:31209045 HLA-C [-27481bp] C - 12 A vs. G 0.433 (G) 0.45 (A) <1 (-) 33 (-) <0.05
rs139587602 chr6:31210279 HLA-C [-26247bp] C - 12 T vs. C - - >1 (-) 0 (-) <0.05
rs3130515 chr6:31190122 HCG27 [+18377bp] All: C 103,235 14 C vs. T - - 0.92 (0.88-0.97) 5 (0-57) 6.42e-04
rs3130406 chr6:31209839 HLA-C [-26687bp] C - 12 A vs. G 0.4 (G) 0.308 (G) <1 (-) 30 (-) <0.05
rs116011117 chr6:31194753 HCG27 [+23008bp] C - 12 T vs. C 0.033 (C) - <1 (-) 0 (-) <0.05
rs2853922 chr6:31266190 HLA-C [+26283bp] All: C 103,235 14 A vs. G 0.425 (A) 0.292 (A) 1.06 (1.02-1.09) 10 (0-49) 7.05e-04
rs3130516 chr6:31190128 HCG27 [+18383bp] All: C 103,235 14 C vs. T - - 0.93 (0.88-0.97) 3 (0-56) 7.07e-04
rs3130436 chr6:31220783 HLA-C [-15743bp] All: C 91,003 11 G vs. A 0.225 (G) 0.333 (G) 1.10 (1.04-1.16) 0 (0-37) 7.09e-04
rs2394893 chr6:31206719 HLA-C [-29807bp] C - 12 A vs. G 0.417 (G) 0.367 (G) <1 (-) 0 (-) <0.05
rs2524066 chr6:31269154 HLA-C [+29247bp] All: C 103,235 14 T vs. C 0.425 (T) 0.283 (T) 1.06 (1.02-1.09) 11 (0-50) 7.35e-04
rs114210995 chr6:31210638 HLA-C [-25888bp] C - 11 A vs. G 0.033 (A) 0.017 (A) >1 (-) 0 (-) <0.05
rs2853918 chr6:31268620 HLA-C [+28713bp] All: C 103,235 14 C vs. T 0.425 (C) 0.283 (C) 1.06 (1.02-1.09) 9 (0-46) 7.48e-04
rs2394901 chr6:31214353 HLA-C [-22173bp] C - 9 T vs. G 0.408 (T) 0.308 (T) >1 (-) 0 (-) <0.05
rs3130432 chr6:31219357 HLA-C [-17169bp] C - 10 A vs. G 0.4 (A) 0.408 (A) <1 (-) 24 (-) <0.05
rs11967684 chr6:31199766 HCG27 [+28021bp] All: C 103,235 14 A vs. G 0.358 (A) 0.308 (A) 0.95 (0.91-0.98) 13 (0-51) 7.91e-04
rs149162659 chr6:31191744 HCG27 [+19999bp] C - 12 A vs. G - - >1 (-) 0 (-) <0.05
rs28570051 chr6:31210601 HLA-C [-25925bp] C - 12 T vs. C 0.4 (T) 0.408 (T) <1 (-) 37 (-) <0.05
rs3134749 chr6:31219469 HLA-C [-17057bp] C - 10 T vs. C 0.4 (T) 0.408 (T) <1 (-) 19 (-) <0.05
rs115878234 chr6:31192110 HCG27 [+20365bp] C - 12 A vs. G 0.033 (A) - >1 (-) 0 (-) <0.05
rs3095250 chr6:31208340 HLA-C [-28186bp] C - 12 T vs. C 0.408 (C) 0.417 (C) <1 (-) 30 (-) <0.05
rs2394943 chr6:31220388 HLA-C [-16138bp] All: C 91,003 11 T vs. C 0.25 (T) 0.467 (T) 1.09 (1.04-1.15) 0 (0-41) 8.47e-04
rs2853921 chr6:31267061 HLA-C [+27154bp] All: C 103,235 14 A vs. G 0.425 (A) 0.3 (A) 1.06 (1.02-1.09) 10 (0-48) 8.47e-04
rs115057643 chr6:31188995 HCG27 [+17250bp] C - 12 C vs. G 0.033 (C) - >1 (-) 0 (-) <0.05
rs3130535 chr6:31209947 HLA-C [-26579bp] C - 12 A vs. T 0.408 (A) 0.3 (A) >1 (-) 33 (-) <0.05
rs6928399 chr6:31195218 HCG27 [+23473bp] All: C 103,235 14 T vs. C 0.358 (T) 0.308 (T) 0.95 (0.91-0.98) 1 (0-55) 8.72e-04
rs1986997 chr6:31228410 HLA-C [-8116bp] All: C 73,373 4 T vs. C 0.417 (T) 0.308 (T) 1.11 (1.04-1.18) 42 (0-81) 8.79e-04
rs9264189 chr6:31220163 HLA-C [-16363bp] All: C 91,003 11 A vs. C 0.225 (A) 0.467 (A) 1.09 (1.04-1.15) 0 (0-36) 9.12e-04

Association studies for this region [+]