HLA-DQA2, chr6:32709119-32714992 +/- 50000 base pairs
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Most significant meta-analysis in this region
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Polymorphism Location (hg19) Gene Ethnicity # Samples # Studies Allele contrast 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs9275326 chr6:32666660 HLA-DQB1 [+30500bp] All: C 99,286 13 T vs. C 0.175 (T) 0.083 (T) 0.80 (0.75-0.85) 2 (0-58) 5.81e-13
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All meta-analyses in this region

Polymorphism Location (hg19) Gene Ethnicity # Samples # Studies Allele contrast 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs2856667 chr6:32665079 HLA-DQB1 [+28919bp] All: C 103,235 14 C vs. T 0.45 (C) 0.267 (T) 0.95 (0.92-0.98) 17 (0-55) 6.43e-04
rs9275593 chr6:32680843 HLA-DQA2 [-28276bp] All: C 99,286 13 A vs. G 0.317 (A) 0.2 (A) 0.93 (0.90-0.97) 67 (41-82) 6.67e-04
rs9275590 chr6:32680480 HLA-DQA2 [-28639bp] All: C 99,286 13 C vs. T 0.308 (C) 0.192 (C) 0.94 (0.90-0.97) 67 (41-82) 7.18e-04
rs9275595 chr6:32681355 HLA-DQA2 [-27764bp] All: C 99,286 13 C vs. T 0.308 (C) 0.2 (C) 0.94 (0.90-0.97) 66 (39-81) 7.97e-04
rs7745040 chr6:32664332 HLA-DQB1 [+28172bp] All: C 103,235 14 C vs. T 0.375 (C) 0.483 (T) 0.95 (0.91-0.98) 0 (0-34) 8.01e-04
rs9275582 chr6:32680070 HLA-DQA2 [-29049bp] All: C 99,286 13 T vs. C 0.308 (T) 0.2 (T) 0.94 (0.90-0.97) 67 (42-82) 8.28e-04
rs2894380 chr6:32664675 HLA-DQB1 [+28515bp] All: C 103,235 14 G vs. A 0.375 (G) 0.475 (A) 0.95 (0.92-0.98) 0 (0-32) 8.29e-04
rs9275571 chr6:32678847 HLA-DQA2 [-30272bp] All: C 103,235 14 G vs. T 0.308 (G) 0.242 (G) 0.94 (0.90-0.97) 64 (36-80) 8.31e-04
rs6457622 chr6:32664163 HLA-DQB1 [+28003bp] All: C 103,235 14 C vs. A 0.358 (C) 0.483 (A) 0.95 (0.92-0.98) 0 (0-33) 8.65e-04
rs9275580 chr6:32679462 HLA-DQA2 [-29657bp] All: C 103,235 14 G vs. A 0.308 (G) 0.233 (G) 0.94 (0.90-0.97) 64 (36-80) 9.54e-04
rs13192471 chr6:32671103 HLA-DQB1 [+34943bp] All: C 103,235 14 C vs. T 0.15 (C) 0.167 (C) 1.08 (1.03-1.13) 52 (12-74) 0.001
rs9275561 chr6:32677789 HLA-DQA2 [-31330bp] All: C 103,235 14 T vs. C 0.308 (T) 0.242 (T) 0.94 (0.90-0.98) 64 (37-80) 0.001
rs9275544 chr6:32676353 HLA-DQA2 [-32766bp] All: C 103,235 14 G vs. A 0.308 (G) 0.233 (G) 0.94 (0.90-0.98) 64 (36-80) 0.001
rs28583593 chr6:32695514 HLA-DQA2 [-13605bp] C - 3 T vs. C - - >1 (-) 87 (-) <0.05
rs3104410 chr6:32683324 HLA-DQA2 [-25795bp] C - 10 T vs. C 0.383 (C) 0.067 (C) <1 (-) 0 (-) <0.05
rs3129718 chr6:32659838 HLA-DQB1 [+23678bp] C - 7 T vs. C 0.192 (T) 0.008 (T) >1 (-) 0 (-) <0.05
rs7764856 chr6:32680640 HLA-DQA2 [-28479bp] C - 11 A vs. T 0.408 (A) 0.35 (A) <1 (-) 62 (-) <0.05
rs9276610 chr6:32742095 HLA-DQB2 [+10784bp] C - 12 A vs. T 0.15 (A) - >1 (-) 41 (-) <0.05
rs3104405 chr6:32682308 HLA-DQA2 [-26811bp] C - 11 A vs. C 0.333 (C) 0.317 (C) <1 (-) 9 (-) <0.05
rs112269159 chr6:32698924 HLA-DQA2 [-10195bp] C - 6 T vs. G - 0.033 (G) >1 (-) 81 (-) <0.05
rs77487028 chr6:32698969 HLA-DQA2 [-10150bp] C - 6 A vs. G 0.008 (G) 0.033 (G) >1 (-) 81 (-) <0.05
rs9275289 chr6:32663208 HLA-DQB1 [+27048bp] C - 12 A vs. C 0.342 (C) 0.492 (A) >1 (-) 0 (-) <0.05
rs5000634 chr6:32663564 HLA-DQB1 [+27404bp] C - 12 A vs. G 0.375 (G) 0.475 (A) >1 (-) 0 (-) <0.05
rs6457619 chr6:32663986 HLA-DQB1 [+27826bp] C - 12 C vs. G 0.383 (G) 0.483 (C) >1 (-) 0 (-) <0.05
rs58327373 chr6:32757589 HLA-DOB [-22951bp] C - 12 A vs. T 0.042 (T) 0.058 (T) >1 (-) 0 (-) <0.05
rs57912571 chr6:32750921 HLA-DQB2 [+19610bp] C - 11 A vs. G 0.05 (G) 0.05 (G) >1 (-) 0 (-) <0.05
rs2067578 chr6:32762461 HLA-DOB [-18079bp] C - 12 A vs. G 0.042 (A) - <1 (-) 0 (-) <0.05
rs17840161 chr6:32698603 HLA-DQA2 [-10516bp] C - 4 C vs. G 0.008 (G) 0.042 (G) >1 (-) 87 (-) <0.05
rs9275274 chr6:32662566 HLA-DQB1 [+26406bp] C - 12 C vs. G - - <1 (-) 0 (-) <0.05
rs4947344 chr6:32677846 HLA-DQA2 [-31273bp] C - 12 T vs. C 0.308 (T) 0.333 (T) >1 (-) 19 (-) <0.05
rs112339869 chr6:32700802 HLA-DQA2 [-8317bp] C - 6 C vs. G - 0.033 (C) <1 (-) 82 (-) <0.05
rs9275273 chr6:32662559 HLA-DQB1 [+26399bp] C - 12 A vs. C - - <1 (-) 0 (-) <0.05
rs9275577 chr6:32679345 HLA-DQA2 [-29774bp] C - 12 A vs. T 0.425 (A) 0.408 (A) >1 (-) 71 (-) <0.05
rs9275272 chr6:32662546 HLA-DQB1 [+26386bp] C - 12 C vs. G - - <1 (-) 0 (-) <0.05
rs2856668 chr6:32663606 HLA-DQB1 [+27446bp] C - 12 C vs. G 0.433 (G) 0.242 (G) <1 (-) 38 (-) <0.05
rs2647016 chr6:32663925 HLA-DQB1 [+27765bp] C - 12 A vs. C 0.417 (C) 0.233 (C) <1 (-) 37 (-) <0.05
rs3129720 chr6:32663631 HLA-DQB1 [+27471bp] C - 12 T vs. C 0.3 (T) 0.158 (T) >1 (-) 27 (-) <0.05
rs9276702 chr6:32756741 HLA-DOB [-23799bp] C - 12 A vs. G 0.225 (A) - >1 (-) 20 (-) <0.05
rs2858320 chr6:32661293 HLA-DQB1 [+25133bp] C - 12 A vs. G 0.45 (A) 0.408 (A) >1 (-) 33 (-) <0.05
rs9276189 chr6:32699325 HLA-DQA2 [-9794bp] C - 9 A vs. G 0.158 (A) 0.0 (A) >1 (-) 57 (-) <0.05
rs2647021 chr6:32663151 HLA-DQB1 [+26991bp] C - 12 T vs. C - - >1 (-) 38 (-) <0.05
rs66709408 chr6:32670414 HLA-DQB1 [+34254bp] C - 12 T vs. C 0.15 (T) 0.167 (T) >1 (-) 59 (-) <0.05
rs2647003 chr6:32664880 HLA-DQB1 [+28720bp] C - 12 T vs. G 0.417 (T) 0.233 (T) >1 (-) 36 (-) <0.05
rs2856666 chr6:32665285 HLA-DQB1 [+29125bp] C - 12 T vs. G 0.408 (G) 0.233 (G) <1 (-) 36 (-) <0.05
rs2647001 chr6:32665086 HLA-DQB1 [+28926bp] C - 12 T vs. C 0.417 (C) 0.233 (C) <1 (-) 36 (-) <0.05
rs9275322 chr6:32666560 HLA-DQB1 [+30400bp] C - 12 C vs. G 0.325 (G) 0.292 (G) >1 (-) 66 (-) <0.05
rs2858317 chr6:32662280 HLA-DQB1 [+26120bp] C - 12 A vs. C - - <1 (-) 39 (-) <0.05
rs2646998 chr6:32665367 HLA-DQB1 [+29207bp] C - 12 T vs. G 0.425 (T) 0.242 (T) >1 (-) 36 (-) <0.05
rs9275320 chr6:32666469 HLA-DQB1 [+30309bp] C - 12 A vs. C 0.317 (C) 0.275 (C) >1 (-) 60 (-) <0.05
rs9276710 chr6:32757102 HLA-DOB [-23438bp] C - 12 T vs. C 0.175 (C) 0.075 (C) >1 (-) 24 (-) <0.05

Association studies for this region [+]