rs3759663, chr14:55370680 (GCH1 [+1110bp])

View on: ALSGene

Forest plot for this polymorphism

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Polymorphism	Location (hg19)	Gene	Allele contrast	Ethnicity	# Studies	# Samples	1000G CEU	1000G CHB+JPT	Meta OR (95%CI)	I2 (95%CI)	Meta P-value
rs3759663	chr14:55370680	GCH1 [+1110bp]	C vs. A	All: C	15	108,990	-	-	1.11 (1.07-1.16)	42 (0-69)	1.06e-06

Association studies for this polymorphism [-][+]

Study	PubMed	Title [+]	Ethnicity	Population	# Cases	# Controls
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	23andMe.v2 (USA, Europe)	3,261	29,499
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	23andMe.v3 (USA, Europe)	866	32,538
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	France (IPDGC)	985	1,984
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	Germany (IPDGC)	667	937
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	Iceland (IPDGC-deCODE)	604	4,916
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	Iceland (CHARGE-AGES-RS)	146	5,609
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	Netherlands (IPDGC)	744	2,019
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	UK (IPDGC)	1,705	5,200
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	USA (IPDGC-NIA)	937	1,896
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	USA (Ashkenazi)	268	178
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	USA (NGRC)	1,956	1,982
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	USA (HIHG)	574	619
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	USA (PROGENI-GenePD)	828	852
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	USA (CHARGE-CHS)	107	3,164
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	USA (CHARGE-FHS)	60	3,889