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1.
SNCA
[-19139bp]
2.
MAPT
3.
TMEM175
4.
ASH1L
5.
MCCC1
6.
STK39
[+24494bp]
7.
rs6430538
8.
BST1
9.
NUCKS1
[+4168bp]
10.
TMEM229B
11.
LRRK2
12.
GPNMB
13.
HLA-DQB1
[+30500bp]
14.
rs2414739
15.
BCKDK
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rs9271126, chr6:32576873 (HLA-DQA1 [-19083bp])
View on:
ALSGene
Forest plot for this polymorphism
Append your own data and create meta-analysis
Polymorphism
Location (hg19)
Gene
Allele contrast
Ethnicity
# Studies
# Samples
1000G CEU
1000G CHB+JPT
Meta OR (95%CI)
I2 (95%CI)
Meta P-value
rs9271126
chr6
:
32576873
HLA-DQA1
[-19083bp]
T vs. G
All: C
4
11,858
-
-
0.76 (0.67-0.85)
22 (0-88)
5.02e-06
Association studies for this polymorphism
[-]
[+]
Study
PubMed
Title
[+]
Ethnicity
Population
# Cases
# Controls
Nalls
,
2014
-
Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci
[-]
Large Scale Meta Analysis of Genome-...
[+]
C
France (IPDGC)
985
1,984
Nalls
,
2014
-
Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci
[-]
Large Scale Meta Analysis of Genome-...
[+]
C
USA (NGRC)
1,956
1,982
Nalls
,
2014
-
Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci
[-]
Large Scale Meta Analysis of Genome-...
[+]
C
USA (PROGENI-GenePD)
828
852
Nalls
,
2014
-
Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci
[-]
Large Scale Meta Analysis of Genome-...
[+]
C
USA (CHARGE-CHS)
107
3,164
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