Study: Nalls, 2014

Population Ethnicity Diagnosis Source # Cases (% women) # Controls (% women) AAO (sd) AAO range AAE (sd) AAE range Ctrl age (sd) Ctrl age range # Polymorphisms
USA (CHARGE-CHS) C self-report, ICD-9, medications PO 107 (45%) 3164 (61%) 73 (5) - - - 72 (5) - 9,655

Polymorphisms in this population [-]

Polymorphism Location (hg19) Gene Allele contrast Ethnicity # Studies # Samples 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs6424234 chr1:232670114 SIPA1L2 C vs. T All: C 15 108,990 0.183 (C) 0.325 (T) 1.09 (1.05-1.14) 27 (0-61) 6.29e-06
rs7532227 chr1:232670146 SIPA1L2 A vs. G All: C 15 108,990 0.183 (A) 0.35 (G) 1.09 (1.05-1.14) 27 (0-61) 5.93e-06
rs3007316 chr1:246873394 SCCPDH [-13955bp] T vs. C All: C 15 108,990 0.358 (T) 0.267 (T) 1.07 (1.04-1.11) 0 (0-43) 4.87e-05
rs3007317 chr1:246875832 SCCPDH [-11517bp] T vs. G All: C 15 108,990 - - 0.94 (0.91-0.97) 0 (0-46) 4.80e-04
rs61813890 chr1:248356884 OR2M3 [-9448bp] A vs. G All: C 14 103,470 - - 0.90 (0.86-0.95) 45 (0-71) 6.13e-05
rs9268996 chr2:17874650 SMC6 C vs. T All: C 5 45,262 - - 1.14 (1.06-1.23) 0 (-) 4.85e-04
rs13402438 chr2:26191490 KIF3C A vs. G All: C 15 108,990 0.325 (A) 0.067 (A) 1.08 (1.04-1.12) 13 (0-51) 2.78e-05
rs13003310 chr2:26200972 KIF3C T vs. G All: C 15 108,990 0.333 (T) 0.042 (T) 1.07 (1.03-1.11) 0 (0-46) 3.81e-04
rs12434584 chr2:29918951 ALK C vs. T All: C 14 105,041 - - 1.07 (1.04-1.11) 0 (0-47) 7.52e-05
rs725631 chr2:31781026 intergenic A vs. C All: C 15 108,990 0.283 (A) 0.492 (C) 0.93 (0.90-0.96) 0 (0-47) 3.23e-05
rs12467911 chr2:31782791 intergenic T vs. C All: C 15 108,990 0.217 (T) 0.45 (T) 0.93 (0.90-0.96) 0 (0-45) 3.19e-05
rs2754530 chr2:31803403 intergenic T vs. C All: C 13 100,707 0.225 (T) 0.45 (T) 0.94 (0.90-0.97) 0 (0-37) 3.52e-04
rs2268799 chr2:31803495 intergenic T vs. C All: C 15 108,990 0.225 (T) 0.45 (T) 0.93 (0.90-0.97) 0 (0-28) 5.43e-05
rs522638 chr2:31805675 intergenic A vs. G All: C 15 108,990 0.225 (A) 0.442 (A) 0.93 (0.90-0.96) 0 (0-43) 2.84e-05
rs806645 chr2:31807940 intergenic T vs. C All: C 15 108,990 0.225 (T) 0.45 (T) 0.93 (0.90-0.96) 0 (0-22) 4.35e-05
rs676033 chr2:31808970 intergenic T vs. C All: C 15 108,990 0.217 (T) 0.45 (T) 0.93 (0.90-0.96) 0 (0-41) 2.40e-05
rs633376 chr2:31815191 intergenic T vs. G All: C 15 108,990 0.233 (T) 0.45 (T) 0.93 (0.89-0.96) 0 (0-39) 7.78e-05
rs809364 chr2:31815453 intergenic G vs. A All: C 15 108,990 - - 1.08 (1.04-1.12) 0 (0-48) 4.89e-05
rs646674 chr2:31815844 intergenic G vs. A All: C 15 108,990 - - 1.09 (1.05-1.13) 0 (0-47) 2.44e-05
rs1090846 chr2:31816341 intergenic C vs. T All: C 15 108,990 - - 1.08 (1.04-1.13) 0 (0-45) 2.54e-05
rs669347 chr2:31830912 intergenic T vs. C All: C 15 108,990 0.225 (T) 0.4 (T) 0.93 (0.89-0.96) 0 (0-51) 3.12e-05
rs607294 chr2:31832807 intergenic T vs. C All: C 15 108,990 0.258 (T) 0.458 (T) 0.93 (0.90-0.96) 0 (0-41) 2.94e-05
rs623419 chr2:31834078 intergenic A vs. G All: C 15 108,990 0.225 (A) 0.45 (A) 0.93 (0.90-0.96) 0 (0-40) 3.58e-05
rs655548 chr2:31836658 intergenic A vs. C All: C 15 108,990 0.233 (A) 0.45 (A) 0.93 (0.90-0.97) 0 (0-30) 7.35e-05
rs534999 chr2:31844504 intergenic T vs. C All: C 15 108,990 - 0.492 (C) 1.07 (1.03-1.11) 0 (0-43) 1.70e-04
rs477517 chr2:31848637 intergenic C vs. T All: C 15 108,990 0.242 (C) 0.467 (C) 0.93 (0.89-0.96) 0 (0-47) 1.63e-05
rs660558 chr2:31850035 intergenic A vs. G All: C 15 108,990 - - 1.08 (1.04-1.11) 0 (0-42) 2.87e-05
rs614173 chr2:31853202 intergenic C vs. T All: C 15 108,990 0.233 (C) 0.458 (C) 0.93 (0.90-0.96) 0 (0-41) 1.96e-05
rs546935 chr2:31853674 intergenic A vs. G All: C 15 108,990 0.208 (A) 0.467 (A) 0.93 (0.89-0.96) 0 (0-42) 2.25e-05
rs644103 chr2:31855321 intergenic G vs. T All: C 15 108,990 0.267 (G) 0.458 (G) 0.94 (0.91-0.97) 0 (0-42) 1.89e-04
rs481344 chr2:31859919 intergenic A vs. G All: C 15 108,990 0.192 (A) 0.442 (A) 0.93 (0.90-0.96) 0 (0-32) 4.10e-05
rs527112 chr2:31865618 intergenic T vs. C All: C 15 108,990 0.2 (T) 0.45 (T) 0.93 (0.90-0.96) 0 (0-44) 2.39e-05
rs569320 chr2:31868047 intergenic T vs. C All: C 15 108,990 0.208 (T) 0.433 (T) 0.93 (0.89-0.96) 0 (0-37) 2.91e-05
rs681482 chr2:31871256 intergenic A vs. G All: C 15 108,990 0.25 (A) 0.458 (A) 0.93 (0.90-0.97) 0 (0-19) 8.03e-05
rs682895 chr2:31871583 intergenic T vs. G All: C 15 108,990 0.225 (T) 0.45 (T) 0.93 (0.90-0.96) 0 (0-42) 3.16e-05
rs539213 chr2:31876492 intergenic G vs. A All: C 15 108,990 0.267 (G) 0.458 (G) 0.94 (0.90-0.97) 0 (0-31) 9.74e-05
rs6748639 chr2:31922672 intergenic T vs. C All: C 15 108,990 0.208 (T) 0.45 (T) 0.92 (0.89-0.96) 0 (0-50) 4.38e-05
rs12479192 chr2:31923042 intergenic T vs. C All: C 15 108,990 0.192 (T) 0.45 (T) 0.92 (0.89-0.96) 0 (0-45) 3.13e-05
rs1510917 chr2:31928899 intergenic A vs. G All: C 15 108,990 0.208 (A) 0.458 (A) 0.92 (0.89-0.96) 0 (0-48) 3.12e-05
rs11683744 chr2:31985308 intergenic T vs. C All: C 15 108,990 0.192 (T) 0.45 (C) 0.92 (0.89-0.96) 0 (0-53) 2.40e-05
rs11124270 chr2:32003345 intergenic A vs. G All: C 15 108,990 0.217 (A) 0.367 (A) 0.93 (0.90-0.96) 2 (0-54) 7.50e-05
rs6726908 chr2:32008223 intergenic T vs. C All: C 15 108,990 - - 1.07 (1.04-1.11) 0 (0-43) 1.12e-04
rs10153876 chr2:32011477 intergenic C vs. T All: C 15 108,990 0.217 (C) 0.408 (C) 0.92 (0.89-0.96) 6 (0-56) 2.16e-05
rs1817437 chr2:32016460 intergenic T vs. C All: C 15 108,990 0.217 (T) 0.392 (T) 0.93 (0.90-0.96) 0 (0-49) 4.21e-05
rs1580329 chr2:32016677 intergenic G vs. A All: C 15 108,990 0.217 (G) 0.467 (G) 0.93 (0.90-0.96) 0 (0-49) 3.60e-05
rs223675 chr2:32026249 intergenic G vs. A All: C 15 108,990 - - 1.08 (1.04-1.12) 0 (0-33) 7.11e-05
rs4952244 chr2:32036625 intergenic A vs. G All: C 15 108,990 0.192 (A) 0.467 (A) 0.92 (0.89-0.95) 5 (0-56) 6.91e-06
rs1119292 chr2:32045773 MEMO1 [-44356bp] T vs. C All: C 15 108,990 0.208 (T) 0.458 (T) 0.92 (0.89-0.96) 5 (0-56) 1.18e-05
rs7587666 chr2:32055890 MEMO1 [-34239bp] T vs. C All: C 15 108,990 0.192 (T) 0.442 (T) 0.92 (0.89-0.96) 0 (0-53) 1.03e-05
rs11904162 chr2:32070489 MEMO1 [-19640bp] G vs. A All: C 15 108,990 0.233 (G) 0.117 (A) 0.93 (0.90-0.97) 0 (0-44) 6.85e-05