Study: Nalls, 2014

Population Ethnicity Diagnosis Source # Cases (% women) # Controls (% women) AAO (sd) AAO range AAE (sd) AAE range Ctrl age (sd) Ctrl age range # Polymorphisms
Iceland (CHARGE-AGES-RS) C ICD codes, medication PO 146 (55%) 5609 (59%) 75 (8) - - - 69 (9) - 8,205

Polymorphisms in this population [-]

Polymorphism Location (hg19) Gene Allele contrast Ethnicity # Studies # Samples 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs10220344 chrY:19917246 RNU1-128P [+16204bp] T vs. C All: C 15 108,990 - - 1.15 (1.10-1.20) 34 (0-64) 2.39e-10
rs11626155 chrY:19917330 RNU1-128P [+16288bp] C vs. T All: C 15 108,990 - - 1.11 (1.06-1.16) 34 (0-65) 2.32e-06
rs62184162 chrY:23228806 intergenic T vs. C All: C 15 108,990 - - 1.09 (1.04-1.13) 0 (0-42) 6.18e-05
rs3997869 - HLA-B C vs. T All: C 14 105,041 - - 1.18 (1.13-1.24) 37 (0-67) 1.94e-11
rs504594 - HLA-DRB1 C vs. A All: C 13 104,595 - - 1.24 (1.17-1.32) 36 (0-67) 5.73e-13