Study: Nalls, 2014

Population Ethnicity Diagnosis Source # Cases (% women) # Controls (% women) AAO (sd) AAO range AAE (sd) AAE range Ctrl age (sd) Ctrl age range # Polymorphisms
Iceland (IPDGC-deCODE) C UKPDSBB CL 604 (48%) 4916 (57%) 62 (12) - - - 80 (8) - 9,406

Polymorphisms in this population [-]

Polymorphism Location (hg19) Gene Allele contrast Ethnicity # Studies # Samples 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs62305151 chr1:91598003 intergenic T vs. G All: C 15 108,990 - - 1.17 (1.10-1.25) 53 (16-74) 2.52e-06
rs58992937 chr1:93099131 EVI5 C vs. T All: C 15 108,990 - - 1.15 (1.09-1.22) 45 (0-70) 6.60e-07
rs7529535 chr1:152605607 LCE3A [+10028bp] A vs. C All: C 15 108,990 0.367 (A) 0.242 (A) 0.92 (0.88-0.96) 26 (0-60) 7.66e-05
rs7545817 chr1:152607331 LCE3A [+11752bp] G vs. T All: C 15 108,990 0.383 (G) 0.25 (G) 0.92 (0.89-0.96) 34 (0-65) 1.60e-04
rs116286121 chr1:154806908 KCNN3 T vs. G All: C 13 101,770 0.017 (T) - 1.47 (1.26-1.73) 0 (0-38) 1.52e-06
rs116839452 chr1:154837939 KCNN3 G vs. A All: C 14 105,041 0.017 (G) - 1.45 (1.23-1.71) 0 (0-22) 6.41e-06
rs114138760 chr1:154898185 PMVK C vs. G All: C 14 105,041 0.017 (C) - 1.50 (1.27-1.77) 0 (0-24) 2.18e-06
rs11264304 chr1:155033317 ADAM15 T vs. C All: C 15 108,990 0.283 (T) 0.083 (T) 1.09 (1.05-1.13) 0 (0-51) 1.77e-06
rs11264305 chr1:155033572 ADAM15 A vs. G All: C 15 108,990 0.267 (A) 0.0 (A) 1.09 (1.05-1.12) 1 (0-54) 1.90e-06
rs35902694 chr1:155042886 EFNA3 T vs. G All: C 15 108,990 0.333 (T) 0.092 (T) 1.07 (1.04-1.10) 0 (0-52) 5.47e-05
rs35682329 chr1:155121143 RNU7-150P [+5335bp] A vs. G All: C 14 105,041 - - 0.54 (0.47-0.61) 0 (-) 3.67e-20
rs35749011 chr1:155135036 KRTCAP2 [-6848bp] G vs. A All: C 13 104,595 - - 0.57 (0.51-0.64) 0 (0-23) 6.10e-23
rs34372695 chr1:156030037 RAB25 [-914bp] C vs. T All: C 15 108,990 - - 0.66 (0.60-0.74) 0 (0-27) 3.31e-14
rs71630614 chr1:156072217 LMNA T vs. C All: C 15 108,990 0.017 (T) - 1.48 (1.33-1.65) 0 (0-25) 2.39e-13
rs76719272 chr1:156129796 SEMA4A T vs. C All: C 15 108,990 0.15 (T) - 0.92 (0.87-0.97) 0 (0-40) 0.001
rs114417629 chr1:156158777 SLC25A44 [-5103bp] A vs. G All: C 15 108,990 0.2 (A) - 0.91 (0.86-0.96) 13 (0-51) 5.26e-04
rs9468618 chr1:158188510 CD1D [+33824bp] C vs. T All: C 14 103,235 - - 1.11 (1.04-1.19) 0 (0-53) 9.62e-04
rs7551957 chr1:161470042 FCGR2A [-5178bp] C vs. T All: C 15 108,990 0.5 (C) 0.225 (C) 1.08 (1.04-1.11) 0 (0-36) 7.06e-06
rs6671847 chr1:161478810 FCGR2A G vs. A All: C 15 108,990 0.492 (G) 0.225 (A) 0.93 (0.90-0.96) 0 (0-33) 9.14e-06
rs4657041 chr1:161478859 FCGR2A T vs. C All: C 15 108,990 0.483 (T) 0.25 (C) 0.93 (0.90-0.96) 0 (0-32) 1.13e-06
rs1801274 chr1:161479745 FCGR2A A vs. G All: C 15 108,990 0.492 (A) 0.25 (G) 0.93 (0.90-0.96) 0 (0-32) 1.19e-06
rs11801283 chr1:171649458 VAMP4 [-19842bp] T vs. C All: C 15 108,990 0.125 (T) 0.142 (T) 0.92 (0.88-0.96) 21 (0-57) 9.77e-05
rs11802265 chr1:171649936 VAMP4 [-19364bp] G vs. A All: C 15 108,990 0.133 (G) 0.108 (G) 0.92 (0.88-0.96) 22 (0-58) 2.83e-05
rs11802686 chr1:171650001 VAMP4 [-19299bp] C vs. T All: C 15 108,990 0.075 (C) 0.092 (C) 0.90 (0.86-0.95) 27 (0-61) 5.17e-05
rs11802687 chr1:171650002 VAMP4 [-19298bp] C vs. T All: C 15 108,990 0.075 (C) 0.108 (C) 0.90 (0.86-0.95) 27 (0-61) 5.15e-05
rs10913475 chr1:171650139 VAMP4 [-19161bp] T vs. C All: C 15 108,990 0.133 (T) 0.133 (T) 0.92 (0.88-0.96) 17 (0-55) 2.89e-05
rs6687922 chr1:171650485 VAMP4 [-18815bp] G vs. A All: C 15 108,990 - - 1.09 (1.05-1.14) 15 (0-53) 3.11e-05
rs6688018 chr1:171650545 VAMP4 [-18755bp] G vs. A All: C 15 108,990 - - 1.09 (1.05-1.14) 17 (0-54) 2.81e-05
rs12125429 chr1:171651153 VAMP4 [-18147bp] C vs. T All: C 15 108,990 0.133 (C) 0.133 (C) 0.92 (0.88-0.96) 17 (0-54) 2.84e-05
rs56345529 chr1:171651372 VAMP4 [-17928bp] T vs. G All: C 15 108,990 0.133 (T) 0.142 (T) 0.92 (0.88-0.96) 16 (0-53) 3.34e-05
rs56091821 chr1:171651434 VAMP4 [-17866bp] T vs. C All: C 15 108,990 0.133 (T) 0.133 (T) 0.92 (0.88-0.96) 16 (0-54) 2.83e-05
rs111668989 chr1:171651950 VAMP4 [-17350bp] T vs. G All: C 15 108,990 - - 1.10 (1.05-1.14) 21 (0-57) 3.29e-05
rs9662174 chr1:171652144 VAMP4 [-17156bp] T vs. C All: C 15 108,990 0.133 (T) 0.133 (T) 0.92 (0.88-0.96) 16 (0-54) 2.73e-05
rs9661596 chr1:171652664 VAMP4 [-16636bp] A vs. G All: C 15 108,990 0.133 (A) 0.133 (A) 0.92 (0.88-0.96) 16 (0-53) 2.69e-05
rs9662853 chr1:171652731 VAMP4 [-16569bp] G vs. A All: C 15 108,990 0.125 (G) 0.133 (G) 0.92 (0.88-0.95) 14 (0-52) 2.41e-05
rs11811780 chr1:171652759 VAMP4 [-16541bp] G vs. A All: C 15 108,990 0.133 (G) 0.133 (G) 0.92 (0.88-0.95) 14 (0-52) 2.73e-05
rs11799420 chr1:171652978 VAMP4 [-16322bp] C vs. T All: C 15 108,990 0.133 (C) 0.133 (C) 0.92 (0.88-0.95) 14 (0-52) 2.44e-05
rs10913489 chr1:171653384 VAMP4 [-15916bp] C vs. T All: C 15 108,990 0.133 (C) 0.108 (C) 0.92 (0.88-0.95) 15 (0-53) 2.87e-05
rs10913490 chr1:171653401 VAMP4 [-15899bp] T vs. G All: C 15 108,990 0.133 (T) 0.108 (T) 0.92 (0.88-0.96) 15 (0-53) 3.21e-05
rs10913492 chr1:171653599 VAMP4 [-15701bp] A vs. G All: C 15 108,990 0.117 (A) 0.133 (A) 0.92 (0.88-0.96) 16 (0-54) 2.92e-05
rs11576221 chr1:171653696 VAMP4 [-15604bp] G vs. A All: C 15 108,990 0.133 (G) 0.133 (G) 0.92 (0.88-0.96) 15 (0-53) 2.79e-05
rs6667559 chr1:171653957 VAMP4 [-15343bp] C vs. T All: C 15 108,990 0.133 (C) 0.133 (C) 0.92 (0.88-0.96) 17 (0-54) 2.82e-05
rs6659874 chr1:171654180 VAMP4 [-15120bp] A vs. C All: C 15 108,990 0.133 (A) 0.133 (A) 0.92 (0.88-0.96) 17 (0-54) 2.77e-05
rs6701553 chr1:171654456 VAMP4 [-14844bp] A vs. G All: C 15 108,990 0.133 (A) 0.117 (A) 0.92 (0.88-0.96) 17 (0-54) 2.77e-05
rs142821193 chr1:171663510 VAMP4 [-5790bp] T vs. C All: C 15 108,990 - - 1.10 (1.05-1.14) 41 (0-68) 1.53e-05
rs113462425 chr1:171663674 VAMP4 [-5626bp] A vs. G All: C 15 108,990 - - 1.10 (1.05-1.15) 6 (0-57) 1.95e-05
rs62046907 chr1:171664325 VAMP4 [-4975bp] T vs. C All: C 15 108,990 0.083 (T) 0.108 (T) 1.01 (0.97-1.06) 0 (0-39) 0.696
rs12123727 chr1:171665508 VAMP4 [-3792bp] A vs. G All: C 15 108,990 - - 1.09 (1.05-1.14) 6 (0-56) 4.85e-05
rs10913507 chr1:171666647 VAMP4 [-2653bp] C vs. A All: C 15 108,990 0.158 (C) 0.133 (C) 0.93 (0.89-0.96) 1 (0-54) 7.35e-05
rs11580415 chr1:171666832 VAMP4 [-2468bp] G vs. A All: C 15 108,990 0.133 (G) 0.133 (G) 0.91 (0.88-0.95) 3 (0-55) 1.07e-05