Study: Nalls, 2014

Population Ethnicity Diagnosis Source # Cases (% women) # Controls (% women) AAO (sd) AAO range AAE (sd) AAE range Ctrl age (sd) Ctrl age range # Polymorphisms
USA (IPDGC-NIA) C UKPDSBB CL 937 (40%) 1896 (53%) 58 (13) - - - 63 (10) - 9,622

Polymorphisms in this population [-]

Polymorphism Location (hg19) Gene Allele contrast Ethnicity # Studies # Samples 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs61087958 chr2:135874038 RAB3GAP1 T vs. C All: C 15 108,990 0.117 (T) 0.217 (T) 0.88 (0.84-0.92) 0 (0-45) 1.55e-07
rs6741481 chr2:135874622 RAB3GAP1 G vs. A All: C 15 108,990 0.117 (G) 0.217 (G) 0.88 (0.83-0.92) 0 (0-47) 1.84e-07
rs2290518 chr2:135878814 RAB3GAP1 A vs. G All: C 15 108,990 0.117 (A) 0.217 (A) 0.88 (0.84-0.92) 0 (0-45) 1.91e-07
rs13410870 chr2:135880013 RAB3GAP1 A vs. G All: C 15 108,990 0.117 (A) 0.208 (A) 0.88 (0.84-0.92) 0 (0-45) 1.85e-07
rs6430561 chr2:135885357 RAB3GAP1 T vs. C All: C 15 108,990 0.117 (T) 0.217 (T) 0.88 (0.84-0.92) 0 (0-45) 1.78e-07
rs7603805 chr2:135893853 RAB3GAP1 A vs. G All: C 15 108,990 - - 1.14 (1.08-1.19) 0 (0-45) 2.41e-07
rs6706466 chr2:135895809 RAB3GAP1 G vs. A All: C 14 106,227 0.125 (G) 0.2 (G) 0.88 (0.84-0.93) 0 (0-49) 5.61e-07
rs11897204 chr2:135899069 RAB3GAP1 T vs. C All: C 14 106,227 - - 1.14 (1.08-1.19) 0 (0-48) 5.52e-07
rs6730157 chr2:135907088 RAB3GAP1 G vs. A All: C 14 108,544 0.267 (G) 0.0 (A) 0.89 (0.86-0.92) 22 (0-58) 9.46e-10
rs4954221 chr2:135909462 RAB3GAP1 A vs. G All: C 15 108,990 0.108 (A) 0.217 (A) 0.88 (0.84-0.92) 0 (0-43) 1.35e-07
rs17261772 chr2:135911422 RAB3GAP1 C vs. T All: C 15 108,990 0.192 (C) 0.0 (T) 0.89 (0.86-0.93) 5 (0-56) 4.35e-09
rs7594509 chr2:135912977 RAB3GAP1 T vs. G All: C 15 108,990 0.117 (T) 0.208 (T) 0.88 (0.84-0.92) 0 (0-42) 1.70e-07
rs11897217 chr2:135914038 RAB3GAP1 T vs. C All: C 15 108,990 0.117 (T) 0.217 (T) 0.88 (0.84-0.92) 0 (0-45) 1.47e-07
rs16831376 chr2:135918681 RAB3GAP1 G vs. A All: C 15 108,990 0.083 (G) 0.175 (G) 0.89 (0.84-0.94) 0 (0-49) 8.92e-05
rs4954224 chr2:135924467 RAB3GAP1 G vs. A All: C 15 108,990 0.075 (G) 0.167 (G) 0.88 (0.83-0.94) 0 (0-49) 9.10e-05
rs6705610 chr2:135925002 RAB3GAP1 G vs. T All: C 15 108,990 0.117 (G) 0.217 (G) 0.88 (0.84-0.92) 0 (0-43) 9.35e-08
rs2305248 chr2:135928312 RAB3GAP1 G vs. A All: C 15 108,990 0.117 (G) 0.217 (G) 0.88 (0.84-0.92) 0 (0-46) 1.27e-07
rs935614 chr2:135932720 RAB3GAP1 G vs. A All: C 15 108,990 0.083 (G) 0.217 (G) 0.88 (0.83-0.93) 0 (0-43) 2.27e-06
rs6716969 chr2:135933317 RAB3GAP1 G vs. A All: C 15 108,990 0.083 (G) 0.217 (G) 0.87 (0.83-0.92) 0 (0-47) 2.23e-06
rs13419577 chr2:135933921 RAB3GAP1 A vs. G All: C 15 108,990 0.083 (A) 0.217 (A) 0.87 (0.83-0.92) 0 (0-45) 1.69e-06
rs74973112 chr2:135934842 ZRANB3 T vs. G All: C 15 108,990 0.083 (T) 0.217 (T) 0.88 (0.83-0.93) 0 (0-45) 2.63e-06
rs6721838 chr2:135935049 ZRANB3 A vs. G All: C 15 108,990 - - 1.14 (1.09-1.20) 0 (0-43) 1.28e-07
rs11897608 chr2:135938999 ZRANB3 T vs. C All: C 15 108,990 0.083 (T) 0.183 (T) 0.89 (0.83-0.94) 0 (0-53) 8.29e-05
rs11903298 chr2:135939824 ZRANB3 G vs. A All: C 15 108,990 0.083 (G) 0.217 (G) 0.88 (0.83-0.93) 0 (0-45) 2.06e-06
rs935612 chr2:135941503 ZRANB3 G vs. A All: C 15 108,990 0.075 (G) 0.167 (G) 0.88 (0.83-0.93) 0 (0-45) 2.02e-06
rs7586126 chr2:135943900 ZRANB3 G vs. A All: C 15 108,990 0.075 (G) 0.167 (G) 0.87 (0.83-0.92) 0 (0-45) 2.06e-06
rs57548051 chr2:135945474 ZRANB3 G vs. A All: C 15 108,990 0.075 (G) 0.125 (G) 0.88 (0.83-0.93) 0 (0-46) 2.44e-06
rs1550983 chr2:135952376 ZRANB3 C vs. T All: C 15 108,990 0.075 (C) 0.167 (C) 0.87 (0.82-0.92) 0 (0-45) 1.39e-06
rs1375131 chr2:135954797 ZRANB3 C vs. T All: C 14 108,544 0.267 (C) 0.0 (T) 0.89 (0.86-0.92) 27 (0-61) 7.53e-10
rs1463136 chr2:135956745 ZRANB3 A vs. G All: C 15 108,990 0.075 (A) 0.167 (A) 0.87 (0.83-0.92) 0 (0-49) 2.39e-06
rs1868320 chr2:135958693 ZRANB3 T vs. C All: C 15 108,990 0.075 (T) 0.167 (T) 0.87 (0.83-0.92) 0 (0-51) 1.86e-06
rs16831429 chr2:135958853 ZRANB3 G vs. T All: C 15 108,990 0.075 (G) 0.167 (G) 0.87 (0.83-0.92) 0 (0-51) 1.88e-06
rs80295457 chr2:135958940 ZRANB3 T vs. C All: C 15 108,990 0.075 (T) 0.133 (T) 0.88 (0.83-0.94) 6 (0-56) 8.05e-05
rs16831433 chr2:135960011 ZRANB3 G vs. T All: C 15 108,990 0.075 (G) 0.133 (G) 0.88 (0.83-0.94) 6 (0-57) 7.97e-05
rs4954226 chr2:135962711 ZRANB3 C vs. T All: C 15 108,990 0.108 (C) 0.167 (C) 0.88 (0.84-0.92) 0 (0-50) 1.75e-07
rs4953949 chr2:135963304 ZRANB3 G vs. T All: C 15 108,990 0.075 (G) 0.167 (G) 0.87 (0.83-0.92) 0 (0-51) 1.82e-06
rs143062241 chr2:135964572 ZRANB3 T vs. C All: C 15 108,990 - - 1.13 (1.06-1.20) 7 (0-43) 7.91e-05
rs16831447 chr2:135966184 ZRANB3 A vs. C All: C 15 108,990 0.075 (A) 0.092 (A) 0.88 (0.83-0.94) 7 (0-43) 7.81e-05
rs6430563 chr2:135967778 ZRANB3 G vs. A All: C 15 108,990 0.075 (G) 0.167 (G) 0.88 (0.83-0.93) 0 (0-53) 7.21e-06
rs73960603 chr2:135971806 ZRANB3 A vs. G All: C 15 108,990 0.075 (A) 0.133 (A) 0.88 (0.83-0.94) 7 (0-43) 7.73e-05
rs10928532 chr2:135972093 ZRANB3 A vs. G All: C 15 108,990 0.075 (A) 0.167 (A) 0.87 (0.83-0.92) 0 (0-53) 1.21e-06
rs16831455 chr2:135973768 ZRANB3 G vs. A All: C 15 108,990 0.067 (G) 0.167 (G) 0.87 (0.83-0.92) 0 (0-50) 1.62e-06
rs60541382 chr2:135975598 ZRANB3 A vs. G All: C 15 108,990 0.067 (A) 0.142 (A) 0.88 (0.83-0.94) 8 (0-45) 6.45e-05
rs4954228 chr2:135976498 ZRANB3 G vs. A All: C 15 108,990 0.075 (G) 0.167 (G) 0.87 (0.83-0.92) 0 (0-50) 1.48e-06
rs16831462 chr2:135978792 ZRANB3 G vs. A All: C 15 108,990 0.075 (G) 0.133 (G) 0.89 (0.83-0.94) 7 (0-44) 8.21e-05
rs1545395 chr2:135980201 ZRANB3 C vs. T All: C 15 108,990 0.075 (C) 0.167 (C) 0.87 (0.83-0.92) 0 (0-50) 1.63e-06
rs4954229 chr2:135980802 ZRANB3 T vs. C All: C 15 108,990 0.075 (T) - 0.89 (0.83-0.94) 7 (0-43) 8.52e-05
rs6430564 chr2:135981554 ZRANB3 G vs. A All: C 15 108,990 0.075 (G) 0.167 (G) 0.87 (0.82-0.92) 0 (0-49) 8.79e-07
rs57829242 chr2:135984172 ZRANB3 G vs. A All: C 15 108,990 0.108 (G) 0.167 (G) 0.88 (0.84-0.92) 0 (0-50) 1.94e-07
rs11892736 chr2:135986636 ZRANB3 C vs. T All: C 15 108,990 0.058 (C) 0.133 (C) 0.88 (0.83-0.94) 8 (0-45) 8.35e-05