Study: Nalls, 2014

Population Ethnicity Diagnosis Source # Cases (% women) # Controls (% women) AAO (sd) AAO range AAE (sd) AAE range Ctrl age (sd) Ctrl age range # Polymorphisms
23andMe.v2 (USA, Europe) C self-reported clinical diagnosis O 3261 (39%) 29499 (42%) 64 (11) - - - 49 (15) - 9,752

Polymorphisms in this population [-]

Polymorphism Location (hg19) Gene Allele contrast Ethnicity # Studies # Samples 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs3997869 - HLA-B C vs. T All: C 14 105,041 - - 1.18 (1.13-1.24) 37 (0-67) 1.94e-11
rs504594 - HLA-DRB1 C vs. A All: C 13 104,595 - - 1.24 (1.17-1.32) 36 (0-67) 5.73e-13