Study: Nalls, 2014

Population Ethnicity Diagnosis Source # Cases (% women) # Controls (% women) AAO (sd) AAO range AAE (sd) AAE range Ctrl age (sd) Ctrl age range # Polymorphisms
23andMe.v3 (USA, Europe) C self-reported clinical diagnosis O 866 (39%) 32538 (40%) 64 (11) - - - 44 (16) - 9,852

Polymorphisms in this population [-]

Polymorphism Location (hg19) Gene Allele contrast Ethnicity # Studies # Samples 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs504594 - HLA-DRB1 C vs. A All: C 13 104,595 - - 1.24 (1.17-1.32) 36 (0-67) 5.73e-13
rs190266 chr17:44019063 MAPT T vs. G All: C 13 97,715 - - 0.82 (0.78-0.86) 26 (0-62) 7.64e-16