rs4478449, chr6:32571801 (HLA-DRB1 [+14176bp])

View on: ALSGene

Forest plot for this polymorphism

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Polymorphism	Location (hg19)	Gene	Allele contrast	Ethnicity	# Studies	# Samples	1000G CEU	1000G CHB+JPT	Meta OR (95%CI)	I2 (95%CI)	Meta P-value
rs4478449	chr6:32571801	HLA-DRB1 [+14176bp]	A vs. G	All: C	5	45,262	0.25 (A)	0.425 (A)	1.24 (1.12-1.36)	57 (0-84)	1.12e-05

Association studies for this polymorphism [-][+]

Study	PubMed	Title [+]	Ethnicity	Population	# Cases	# Controls
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	23andMe.v3 (USA, Europe)	866	32,538
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	France (IPDGC)	985	1,984
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	USA (NGRC)	1,956	1,982
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	USA (PROGENI-GenePD)	828	852
Nalls, 2014	-	Large Scale Meta Analysis of Genome-wide Association Data in Parkinson’s Disease Reveals 6 Novel Risk Loci [-]Large Scale Meta Analysis of Genome-... [+]	C	USA (CHARGE-CHS)	107	3,164