Study: Nalls, 2014

Population Ethnicity Diagnosis Source # Cases (% women) # Controls (% women) AAO (sd) AAO range AAE (sd) AAE range Ctrl age (sd) Ctrl age range # Polymorphisms
Iceland (IPDGC-deCODE) C UKPDSBB CL 604 (48%) 4916 (57%) 62 (12) - - - 80 (8) - 9,406

Polymorphisms in this population [-]

Polymorphism Location (hg19) Gene Allele contrast Ethnicity # Studies # Samples 1000G CEU 1000G CHB+JPT Meta OR (95%CI) I2 (95%CI) Meta P-value
rs854804 chr17:18067404 MYO15A A vs. G All: C 15 108,990 0.35 (A) 0.1 (G) 0.93 (0.90-0.96) 10 (0-47) 8.98e-06
rs854795 chr17:18070062 MYO15A A vs. G All: C 15 108,990 0.35 (A) 0.108 (G) 0.93 (0.90-0.96) 9 (0-46) 9.55e-06
rs8071834 chr17:18099991 ALKBH5 T vs. C All: C 14 106,227 0.358 (T) 0.108 (C) 0.94 (0.91-0.97) 0 (0-54) 1.15e-04
rs4924839 chr17:18103907 ALKBH5 A vs. G All: C 15 108,990 0.358 (A) 0.1 (G) 0.93 (0.90-0.96) 8 (0-45) 1.22e-05
rs1378602 chr17:18111868 ALKBH5 G vs. A All: C 15 108,990 0.358 (G) 0.1 (A) 0.93 (0.90-0.96) 6 (0-57) 1.27e-05
rs8069321 chr17:18117610 ALKBH5 [+4342bp] C vs. T All: C 15 108,990 - - 1.08 (1.04-1.11) 2 (0-55) 1.23e-05
rs1378601 chr17:18121926 LLGL1 [-6975bp] T vs. C All: C 15 108,990 0.367 (T) 0.1 (C) 0.93 (0.90-0.96) 7 (0-44) 7.91e-06
rs12451754 chr17:18124513 LLGL1 [-4388bp] T vs. C All: C 15 108,990 0.433 (T) 0.075 (T) 1.07 (1.03-1.10) 0 (0-39) 9.30e-05
rs12939469 chr17:18124908 LLGL1 [-3993bp] T vs. C All: C 15 108,990 0.442 (T) 0.092 (T) 1.07 (1.03-1.10) 0 (0-39) 9.27e-05
rs4925150 chr17:18125471 LLGL1 [-3430bp] C vs. A All: C 15 108,990 - - 0.94 (0.91-0.97) 0 (0-39) 9.11e-05
rs2605132 chr17:18128474 LLGL1 [-427bp] G vs. A All: C 15 108,990 0.458 (G) 0.075 (G) 1.07 (1.03-1.11) 0 (0-30) 8.60e-05
rs2605134 chr17:18130144 LLGL1 C vs. T All: C 15 108,990 0.358 (C) 0.317 (T) 0.93 (0.90-0.96) 17 (0-54) 4.76e-06
rs2605135 chr17:18131087 LLGL1 T vs. C All: C 15 108,990 0.358 (T) 0.308 (C) 0.93 (0.90-0.96) 16 (0-53) 5.11e-06
rs2746026 chr17:18134354 LLGL1 T vs. C All: C 15 108,990 0.383 (T) 0.308 (C) 0.92 (0.89-0.95) 12 (0-50) 1.47e-06
rs2746028 chr17:18139896 LLGL1 T vs. G All: C 15 108,990 0.383 (T) 0.317 (G) 0.92 (0.89-0.95) 8 (0-45) 6.83e-07
rs2245737 chr17:18144720 LLGL1 C vs. T All: C 15 108,990 0.383 (C) 0.308 (T) 0.92 (0.89-0.95) 15 (0-53) 1.07e-06
rs2473657 chr17:18153301 FLII G vs. A All: C 15 108,990 - - 1.09 (1.05-1.12) 27 (0-61) 7.16e-07
rs62075804 chr17:40599558 RNU7-97P [+7281bp] T vs. G All: C 15 108,990 0.267 (T) 0.025 (T) 1.09 (1.05-1.13) 32 (0-63) 1.50e-06
rs8070757 chr17:40600319 RNU7-97P [+8042bp] C vs. A All: C 15 108,990 - - 0.92 (0.88-0.95) 31 (0-63) 1.19e-06
rs9915118 chr17:40602533 ATP6V0A1 [-8329bp] G vs. A All: C 15 108,990 - - 0.92 (0.89-0.95) 32 (0-64) 1.60e-06
rs9897702 chr17:40609405 ATP6V0A1 [-1457bp] A vs. G All: C 15 108,990 0.258 (A) 0.033 (A) 1.09 (1.05-1.13) 32 (0-63) 1.45e-06
rs9907126 chr17:40613441 ATP6V0A1 C vs. T All: C 15 108,990 0.258 (C) - 1.09 (1.05-1.13) 34 (0-64) 1.36e-06
rs62075812 chr17:40635401 ATP6V0A1 T vs. C All: C 14 105,041 0.2 (T) - 1.10 (1.06-1.15) 0 (0-43) 7.55e-06
rs11653901 chr17:40636168 ATP6V0A1 C vs. T All: C 15 108,990 - - 0.91 (0.88-0.95) 33 (0-64) 1.56e-06
rs12949604 chr17:40644611 ATP6V0A1 C vs. T All: C 15 108,990 - - 0.92 (0.88-0.95) 35 (0-65) 1.20e-06
rs56143576 chr17:40644674 ATP6V0A1 G vs. A All: C 14 105,041 0.117 (G) - 1.11 (1.06-1.17) 0 (0-46) 1.99e-05
rs11651671 chr17:40646803 ATP6V0A1 A vs. G All: C 15 108,990 0.258 (A) 0.033 (A) 1.09 (1.05-1.13) 34 (0-64) 1.06e-06
rs34779517 chr17:40650805 ATP6V0A1 C vs. T All: C 15 108,990 - - 0.91 (0.88-0.94) 29 (0-62) 6.48e-07
rs62075828 chr17:40653534 ATP6V0A1 G vs. A All: C 15 108,990 - - 0.92 (0.88-0.95) 33 (0-64) 1.12e-06
rs2012070 chr17:40657101 ATP6V0A1 G vs. T All: C 15 108,990 0.258 (G) 0.033 (G) 1.09 (1.05-1.13) 34 (0-64) 1.12e-06
rs9904840 chr17:40657577 ATP6V0A1 C vs. T All: C 15 108,990 - - 0.92 (0.88-0.95) 34 (0-64) 9.52e-06
rs4411548 chr17:40658533 ATP6V0A1 T vs. C All: C 15 108,990 0.242 (T) 0.033 (T) 1.09 (1.05-1.13) 34 (0-64) 1.12e-06
rs2354534 chr17:40684176 NAGLU [-4014bp] G vs. A All: C 15 108,990 - - 0.91 (0.87-0.94) 36 (0-65) 1.64e-06
rs601999 chr17:40698158 NAGLU [+1691bp] C vs. T All: C 15 108,990 - - 0.92 (0.89-0.95) 52 (14-73) 1.20e-06
rs2676530 chr17:40705955 HSD17B1 T vs. C All: C 15 108,990 0.233 (T) - 1.10 (1.06-1.15) 35 (0-65) 3.18e-06
rs668799 chr17:40716235 COASY T vs. C All: C 15 108,990 0.325 (T) 0.383 (T) 0.93 (0.90-0.97) 1 (0-54) 8.26e-05
rs646123 chr17:40720632 MLX A vs. G All: C 15 108,990 0.325 (A) 0.383 (A) 0.93 (0.90-0.97) 1 (0-54) 9.69e-05
rs665268 chr17:40722029 MLX G vs. A All: C 15 108,990 0.325 (G) 0.383 (G) 0.93 (0.90-0.97) 1 (0-54) 9.04e-05
rs10454087 chr17:40735641 FAM134C T vs. C All: C 15 108,990 0.325 (T) 0.392 (T) 0.93 (0.90-0.96) 0 (0-53) 7.08e-05
rs12951632 chr17:40741013 FAM134C C vs. T All: C 15 108,990 0.333 (C) 0.392 (C) 0.93 (0.90-0.96) 0 (0-53) 6.67e-05
rs112666141 chr17:40753714 FAM134C G vs. A All: C 15 108,990 - - 1.08 (1.04-1.12) 0 (0-53) 7.42e-05
rs9891536 chr17:40754779 FAM134C G vs. A All: C 15 108,990 - 0.033 (A) 0.92 (0.89-0.95) 40 (0-68) 2.22e-06
rs60929812 chr17:40759448 FAM134C A vs. G All: C 15 108,990 0.325 (A) 0.392 (A) 0.93 (0.90-0.97) 0 (0-52) 8.20e-05
rs11651246 chr17:40759937 FAM134C G vs. T All: C 15 108,990 0.133 (G) - 1.12 (1.06-1.17) 30 (0-62) 2.26e-05
rs4793039 chr17:40760234 FAM134C G vs. A All: C 15 108,990 0.242 (G) - 1.09 (1.05-1.13) 41 (0-68) 2.44e-06
rs74322397 chr17:40768629 TUBG1 [+1377bp] C vs. T All: C 15 108,990 - - 1.07 (1.04-1.11) 0 (0-53) 9.02e-05
rs35635959 chr17:40772288 TUBG1 [+5036bp] C vs. T All: C 15 108,990 0.325 (C) 0.4 (C) 0.93 (0.90-0.96) 0 (0-52) 8.04e-05
rs62078394 chr17:40772967 TUBG1 [+5715bp] A vs. C All: C 15 108,990 0.25 (A) - 1.09 (1.05-1.13) 41 (0-68) 2.72e-06
rs12601457 chr17:40780847 TUBG1 [+13595bp] C vs. T All: C 15 108,990 - 0.392 (T) 1.08 (1.04-1.12) 1 (0-54) 7.98e-05
rs34138141 chr17:40781561 TUBG1 [+14309bp] T vs. G All: C 15 108,990 0.325 (T) 0.2 (T) 0.93 (0.90-0.96) 0 (0-53) 9.03e-05